Salutations!

It is safe to say that most of the "news" relating to health we receive today is nothing more than cleverly disguised advertisements for various products or unhealthy modalities that aren't very good for you. Unfortunately this "news" is often the only side of the story we receive and because of this we can not make informed decisions. My prayer is that through a network of concerned persons we can present the "other side" of the story in a way that would educate and convict us so that a not-so- educated guess given by others becomes an informed decision made by you.







Monday, April 7, 2014

Medical Conspiracies - Are We the Crazy Ones?





I would like to start this article with a true story whose point will become clear a little later so please bear with me. In 1932 the U.S. Public Health Service began a clinical trial to track the natural progression of a disease known as syphilis. History records that a total of 600 men “participated” in the study. You will notice that the word participated is in quotes. That is because the men were not told they were participating in a syphilis experiment (more on this later). 301 of the men contracted syphilis before the study and the other 299 afterwards because they were intentionally infected. None of the men were told they had syphilis and treatment was withheld which was ultimately a death sentence for most. At the time of the trial there were no known cures but a few treatments were available. Left untreated syphilis can ultimately lead to senility, organ failure and death. Ironically, sadistically, and sadly, free burial insurance was given to all participants. The study lasted 40 years even after a new and successful form of treatment was discovered.

An article recently went out through the mainstream media (Rueters, Associated Press, etc) about medical conspiracies and how many Americans believe them. In a nutshell the premise is this: Medical conspiracies do not happen and if you believe in them you should have your head examined because you are a total whack job. I will admit the emphasis is mine but one cannot help but draw a similar line to this synopsis due to the tone of the articles. Some of them do graciously point out that most of the people are not completely crazy but just a little crazy. They also tend to be a "little" poor and a "little" uneducated and just to make sure the insults cover as many people as possible they are often minorities (please refer back to the introductory paragraph to possibly explain the last insulting point since it involved African American men exclusively).

There are two issues at hand and they are worth delving into. The first issue is the premise that medical conspiracies do not and have not existed. The second issue is that all conspiracy theorist are tin foil hat wearing goobers and if you happen to believe that it is possible for a group of people to take advantage of another group of people then you are a goober too. Each point will be addressed in detail for our edification and thoughtful analysis.

This article will be in three parts with this being part I. Parts II and III will follow shortly.

Tuesday, March 18, 2014

The Story of Cholesterol: A Supplemental on Supplementals

In the last article (which was supposed to be the last article in this series) we covered the miraculous and beneficial effects of CoQ10 on heart health and energy. If you or a loved one ever had a heart attack CoQ10 supplementation is a must. 

As far as supplements go the story is a bit more involved than just CoQ10 as wonderful as it is. There are a few other supplements that can greatly improve cardiovascular health and increase energy in the process. The news gets even better when you consider that, along with CoQ10, anyone can benefit from a boost of energy and vitality when the following supplements are added to a healthy lifestyle. Just as before in the previous article it is necessary to point out that nothing written here should be construed as medical advice and that any supplemental regimen should be discussed with your trusted (and open minded) healthcare professional. With that caveat established let's take a look at some of the other supplements that you may or may not be familiar with.

D Ribose

We are energetic beings and our bodies need plenty of energy. ATP (adenosine triphosphate) is how our body gets things done energetically speaking. One of the main constituents of ATP is D-ribose. No D-ribose means there can be no way to produce ATP. Without ATP there can be no energy. D-ribose is generated by the body mostly on the as-needed basis and there is no way to store it. This is an important factor to consider because when tissues are under stress they cannot produce D-ribose and thus the body is robbed of energy. The combination of poor heart function leading to oxygen deprivation and the inability to produce energy can leave you feeling quite poor in deed.

A prominent German physiologist by the name of Heinz-Gerd Zimmer established a connection between heart function and D-ribose. He found that people who had hearts deprived of nutrients and oxygen sometimes due to blockages fared better when given D-ribose.  Zimmer also found that the administration of D-ribose had restorative powers for energy and helped bring about normal diastolic heart function. In a 1992 clinical study D-ribose was also shown to have increased the ability to do exercise in patients that had severe coronary artery disease.

Magnesium

One of the main culprits of poor cardiovascular health is actually the inability to properly absorb calcium which is found in plentiful amounts in most western diets. When calcium is ill-absorbed it remains in the blood stream longer where it has a greater chance to interact with free radicals increasing the rate of calcification that often occurs in arteries and other blood vessels. At this point blockages are sure to happen given enough time. This is where magnesium comes in to help. Magnesium, along with vitamin D, helps to convert calcium into a more absorbable form before it calcifies keeping blood vessels clear. If that was not important, or impressive, enough magnesium is also great at keeping platelets from aggregating (sticking together) and forming blood clots while it also acts as a vascular dilator reducing blood pressure. It should be noted that people suffering from renal insufficiencies should not supplement with magnesium without medical guidance.

B Vitamin Complex (especially B5)

B vitamins in and of themselves provides the body with massive, sustained energy over a significant amount of time and that is simply awesome. For the sake of this article, however, we will cover vitamin B5 specifically in a slightly different light. Many people are unaware of the vital role B5 (also known as pantothenic acid) plays in limiting inflammation and oxidation of cholesterol. No less than 28 clinical studies have shown that vitamin B5 produced positive results regarding triglyceride levels and LDL cholesterol levels while increasing HDL levels. A literature review was conducted by Dr. Mark Houston and published in Progress in Cardiovascular Diseases helped establish pantothenic acid’s importance in cardiovascular health. The literature demonstrated after only four months of B5 supplementation total cholesterol was reduced by 15%, LDL cholesterol by 20% and triglycerides by 32.9% while increasing HDL by 8.4%. He also noted that studies of longer duration showed continued improvement in participants over the initial four month successes. Reduce inflammation and you reduce cholesterol…period!

We long to live lives enriched by the fragrance of energy and productivity radiating from every pore. Sometimes, however, devastating health conditions such a heart attack can rob us of that ability leaving one disturbed and down trodden. The beauty of nature and life is that even if we find ourselves in this lowered state of affairs we do not have to dwell there. An out is often provided if we look carefully and thoughtfully at our circumstances. There are, of course, many more supplements that could be considered but this is a healthy start (pun intended). Proper supplementation of the right nutrients can be the difference between slumming in the doldrums and soaring with the eagles after an adverse cardiovascular event. This article should serve as a great catalyst for conversation between you and your trusted healthcare provider.

Sources for this article include:


The Great Cholesterol Myth (Bowden and Sinatra)

Wednesday, March 5, 2014

The Story of Cholesterol: Energy, CoQ10 and Statins



We have reached the point where the discussion turns to the practical side of things. Once the thinking is done we must put into practice what we have learned. Right off the top the need for a disclaimer is paramount: Nothing in this article should be construed as advice on dietary or supplemental modalities. You should consult your physician or a trusted health care provider for your specific needs. In the interest of stimulating a great conversation between you and your health care provider the words that follow should be your guide.

The miracle of Coenzyme Q10 (CoQ10)

One of the main issues surrounding statin drugs is how it inhibits the production of a key enzyme known as CoQ10. Devastating adverse health effects have been associated with CoQ10 deficiencies and has been recognized by some parts of the medical community in the U.S. and more widely in Europe and the Far East. Many people are familiar with the term “CoQ10” but do not have a firm grasp of what it is and how vital it is to our hearts so let’s discuss it.  

CoQ10 is a powerful vitamin-like substance produced by virtually every cell in the body. It has many functions that prove to be vitally important to the body. One of those functions is converting our food into fuel for our cells to use. When we eat good, wholesome foods and CoQ10 is present in the cells in adequate supplies our energy levels rise. The science of the process in which CoQ10 does its work is actually intriguing but we will skip the detailed lesson and just say without it we would have a hard time getting much of anything done. Because the heart is such a dense muscle that is always active it is one of the top CoQ10 producers in the body and rightfully so. Beating on average 2.5 billion times during a person’s life the heart requires a wealth of energy. Statins interfere with the production of some enzymes including CoQ10 robbing the heart of significant amounts of energy. To add insult to injury as we age we tend to produce less and less of this powerful enzyme naturally setting us up for exponential energy lose and poor cardiovascular production.

Another function of this miracle enzyme is blood pressure modification. It has proven itself to be an awesome way to reduce blood pressure without harmful side effects. A meta-analysis of clinical trials conducted in 2007 by F.L. Rosenfeldt et al (Coenzyme Q10 in the treatment of hypertension…) found overwhelming, across the board evidence that significant reductions in blood pressure took place among test subjects taking the supplement when compared to the control group (who did not take CoQ10 at all). Since 1974 doctors in Japan have prescribed CoQ10 to patients who experience congenital heart failure. Further studies in the U.S. showed a marked increase of heart function and vitality in people suffering from severe (class III and class IV) cardiomyopathy. These were people who were given just a year or two to live because they were that sick until CoQ10 supplementation began.

In addition, CoQ10 is a wonderful antioxidant. Oxidative stress, especially as it relates to LDL cholesterol, is a major cardiovascular concern. Remember that cholesterol in and of itself is not the boogey man but oxidized pattern B LDL cholesterol is. Coenzyme Q10 steps in and helps to prevent oxidation of patter B LDL helping to stop the type of cardiovascular stress that plague so many people. A healthy non-inflammation inducing eating plan along with CoQ10 supplementation can make all the difference in having excellent heart health especially if the person is experiencing poor cardiovascular health at the moment.

Where to find it

Typically CoQ10 tends to be found most prevalently in the organ meat of animals such as the kidneys, liver and heart. This is the most natural way to get it from outside your own body. The problem is enzymes tend to breakdown very readily when exposed to high heat even for short periods of time. The alternative to consuming organ meat (especially if you are vegetarian) has to be in the form of a supplement.

CoQ10 supplements are out there but it is imperative you can trust the source. There is no need to consume anything that is of low quality in the hopes that it will be beneficial. High quality CoQ10 that is readily bioavailable is a must. Seek advice from a knowledgeable source when determining what you might like to use.  

In Conclusion

There is a distinct correlation between CoQ10 deficiency and poor, sometimes fatal, heart function. So much so that the evidence of years of studies should be splattered across the headlines daily warning us about the deficiency and how to overcome it through supplementation. Medically speaking it is a very cheap and efficient way to reduce mortality and morbidity from cardiovascular issues especially in comparison to drugs and surgery that both carry ill side effects while draining personal and institutional coffers worldwide.

Originally this was supposed to be the last article in the series but there are other nutrients that should be discussed that would be of great benefit to cardiovascular health. With that thought in mind one or two additional articles may be necessary for the sake of thoroughness.


Sources: The Great Cholesterol Myth (Bowden and Sinatra)

Monday, February 24, 2014

The Story of Cholesterol: The Next Generation (Our Children)

The pharmaceutical industry has its eye on what could be one of the most lucrative demographics that can be tapped into: our children. With obesity rates among young people on a steady rise it was only a matter time before higher cholesterol rates were observed with an eagerness to address it with statin drugs.

Other than the elderly our children are the most vulnerable of us all. That is why special care must be undertaken to ensure a healthy and prosperous start to life. Could statin drug use in our children be the start they need?

The Effects

No one knows for sure the long term effects of statin drugs on children. The reason for this is that no long term studies have been conducted to show efficacy (benefit or harm). What is known is how it affects adults in a relatively short span of time and most often the news is not good.

Also we must consider the fact that statins lower cholesterol by inhibiting the production of hormones especially sex hormones (e.g. testosterone and estrogen). In children this could be potentially devastating altering how their bodies develop forever by interfering with puberty and proper growth. It is known that statin drugs communicate with the pituitary gland blocking or discontinuing certain hormonal functions stunting biological processes.

Children, eating habits, and exercise

According to the Centers for Disease Control childhood obesity rates have doubled in children and tripled in adolescents in the past 30 years. In 2010 it was estimated that nearly 1/3 of all children were overweight or obese. With these statistics there are some doctors and pharmaceutical reps chomping at the bit to get statins into the mouths of children but it doesn't have to be so.

Children tend to eat the way their parents eat. In fact, it is highly likely that if the parents are sedentary, fast food junkies so to will the children likely be. It is estimated that 1/3 of all adults in the U.S. are obese so the estimate for children makes sense. After all the apple doesn't fall far from the tree. We live in a world where we seek the path of least resistance which means we sometimes take short cuts with our health and the health of our children by doing the least possible by way of exercise and activity. We should encourage children to be more active by word and by deed. Children must be told and shown how and why to be active because their very lives depend on it. The same goes for eating habits. A healthy meal plan for the entire family is a great way to get kids involved in healthful and nourishing eating habits that will last their lifetimes.

Medications have their place but long term habitual use in our children will only lead to devastating consequences during or before early adulthood. After all, when you really get down to it, do we really expect an 11 year old child to take statins for 40-60 years without consequences when we know what it does to fully grown adults? Can you imagine the potential profit base for pharmaceutical companies over the same period of time? The average annual per patient cost for a statin is $800 X 60 (years) X 14,000,000 (number of children between the age of 6 and 17 years old that are considered obese or overweight as of 2012) = $672 billion (yes, billion with a B). This number does not take into account the portion of money covered by insurance which is covered by those who pay premiums. It also does not take into account the money that will be spent on other health issues as a result of statin drug use. What is very sad is that the figure above may be overstated because the assumption is a child of 11 would survive until their 70th birthday while taking a statin drug which is unlikely.

More fruits and vegetables, less processed and fast food and a little more movement will allow our children to grow healthy and strong while allowing parents and premium payers alike to keep our money and sanity.


Monday, February 17, 2014

Multivitamin Use Absurd and Dangerous? I Think Not Part II



Another major flaw in the studies cited is what really gives me the greatest concern. With the exception of the chelation study the participants were allowed to use any type of multivitamin they wanted. It mattered not to the researchers if those participating in the studies used natural or synthetic vitamins. The quality of the vitamin nor amount consumed did not matter much either. Participants were not guided on vitamin intake except for the request that the upper limits of vitamin consumption as described by the US Food and Nutrition Board were not exceeded. Even the chelation study failed to control for the quality of the supplements used by the researchers.

A word about "natural" vs. synthetic" vitamins

Since the participants could walk into any store or go online and purchase whatever they wanted there was surely a hodgepodge of vitamins and minerals used. Most people succumb to mainstream advertisements as a major source of supplement information and end up purchasing cheap, synthetic versions of the vitamin they want. The old adage "you get what you pay for" rings very true in this case. Most synthetic vitamins are not bio-available (a fancy word that means your body cannot absorb it) while others are ill absorbed and therefore are just plain trash. How is it possible to receive a meaning outcome in a study where you can shout to the world that multivitamins are useless if you fail to control for (or consider in the case of a meta-analysis) what the participants use? Furthermore, an upper limit of how much to take was established but not a lower limit. What if several of the participants decided to take half doses or less? What reasonable conclusions could one make of a study or analysis that does not account for this? 

It is estimated that a fair majority of all vitamins and minerals on the market today are synthetic with some estimates going as high as 90%! With marketers of all stripes and colors jockeying for our supplemental dollars the truth about the efficacy of their products gets more and more fuzzy. Labels like "all natural" or "food source" can be highly legalistic in definition and therefore deceiving. In order to make sure you are consuming natural vitamins that are high in quality you have to know and trust the manufacturer which can be difficult for sure. Until trust in a product is sure I can give you this one tidbit to take with you on you next supplement shopping trip. Be sure to read the labels and know that any vitamin that begins with "dl" is a synthetic. For example, one of the most widely consumed vitamins in the U.S. is dl-alpha-tocopherol which is a cheap and synthetic form of vitamin E. Notice the "dl" at the head of the name. Also, some manufacturers mix the natural version of a vitamin with the synthetic version. This is how some supplements can be labeled "natural" while containing synthetic product so make sure to read the ingredients if a natural vitamin is what you are looking for.



A holistic approach to health often overlooked

Sadly, many people would like to pigeon hole our health into tidy little compartments mostly to our detriment. Some mean well enough while others are more intentional. Either way we are left in a terrible mess when we or researchers fail to consider the big picture to our health. The interesting point to make here is that multivitamin and mineral use is only one part of the kaleidoscope that makes for great health. If you want to prevent or reverse cardiovascular issues several things must be done. Limiting oxidative stress and inflammation in conjunction with a healthy eating plan, exercise and mental stress mitigation are all keys to better cardiovascular health. I find it extremely disingenuous to conduct any such study of vitamin and mineral use without considering these additional avenues of approach. No one should believe that just taking a multivitamin is going to be helpful while remaining sedentary, over stressed and filled to the gills with fast food especially if the vitamin is synthetic and crappy! But that is just what the researchers want us to believe and what's sad is some of us will.

Sunday, February 9, 2014

Multivitamin Use Absurd and Dangerous? I Think Not Part I



Do you remember Christmas as a child with that jolly red nosed Santa who most kids idolized in every sense of the word? Or maybe for you it was the tooth fairy, the great pumpkin or even Peter Cottontail. Any or all of these myths seemed to be real to us and for some the realization that they don't exist was quite the shock. Banished to the realm of make believe our childhood idols went and now some would have us believe another one of our cherished beliefs (that is actually a fact) should be relegated to the same place we put St. Nick and the others.

Recently several studies were analyzed that purport to firmly establish the "fact" that multivitamin supplementation is at best useless and at worst detrimental to your health to the point of causing harm. Harm from vitamins? Let us explore the article and the studies it cites in an effort to keep vitamin supplementation out of the realm of make believe.

The Researchers

Eliseo Guallar and his colleagues recently analyzed three studies and came to a shocking conclusion. They have stated, unequivocally, that multivitamin supplementation has no clear benefit and could prove harmful to your health. The group of researchers went on to say that multivitamins should not be used in the prevention of chronic disease and that "enough is enough" when it comes to the silly people who erroneously use these vitamins (emphasis mine). After you get past the initial shock that vitamin supplementation is harmful or useless and wrestle with the condescending tone of the abstract written by the researchers you are left to ponder things that you have held to be true: that vitamins are good for you. Should vitamins head off to the island of misfit beliefs with the rest of our childhood idols? Intuitively you know the answer but let us spell a few things out for the sake of clarity and sound reasoning.

The conclusion of these researchers has been published in the Annals of Internal Medicine and is chock full of assumptions. One of these assumptions provided by Guallar et al is that the average western style diet provides adequate nourishment to the masses to the point that vitamin and mineral supplementation is unnecessary. Surely, there are a percentage of westerners who eat pretty healthy by consuming clean, pure water and either natural or organic foods while limiting processed foods but this does not pertain to the vast majority especially in America. In addition, due to soil depletion and over-farming mineral and vitamin levels in fruits, vegetables and grains have been on a decline for decades.

Aside from the assumption let us to take a look at what really lies at the heart of the matter for the people who take great interest in their health. An analysis of the three studies is appropriate and fundamental so we can understand what the researchers saw and what the newspapers, online publishers and television programs failed to report.




The Studies

Three studies were cited by the researchers and here is where we really have to pay attention which is unfortunate. It is unfortunate because there is a sense among most people in the general public that studies are impartial, truthful and therefore should be taken as gospel. Since the word gospel literally means "good news" some of these studies should be taken as the anti-gospel. Let us review

Cardiovascular Disease and Cancer Study

The first study mentioned in the article is the "Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer". I know it's a mouthful but bear with me. Researchers in this study wanted to establish whether cardiovascular issues and cancer was actually preventable through supplementation. It appears to be a noble endeavor on the surface even with flawed results (an explanation on why it is not noble will present itself a little later). It was acknowledged that the results of this study did not pertain to individuals with nutrient deficiencies or others that would be considered high risk. The article cited above would have you believe the results of this trial pertained to everyone. When you consider that most people are nutrient deficient the article becomes just plain misleading.

At one point in the analysis of the trial the researchers had to admit that the study was actually set up to measure results in a drug trial not a nutrient trial which may skew the data. In addition, it was noted that the difference between examining optimal levels of a nutrient intake and "normal" levels may have established a different result. In other words studying minimum nutrient supplementation may not be in the best interest of the general public. Then the question becomes "Why do the study in this way if the results do not apply to most people"? Great question!

Cognitive Function in Men

This study was a misnomer from the very start. Called "Long Term Multivitamin Supplementation and Cognitive Function in Men: A Randomized Trial"  it looked at a very particular group of men: doctors. The importance of this will become clear in a moment. The intent of this study was to assess cognitive function in men and whether multivitamin supplementation would improve it. The conclusion was that multivitamin supplementation does not improve cognitive function or prevent dementia.

There are three interesting points to consider regarding this study. The first is that physicians were studied and this poses a problem. It has been long established that people who pursue academics have a lowered risk of developing dementia. Secondly, most older physicians generally eat very healthy and are able to afford the best, most nutritious foods. Proper nourishment combined with a high level of education diminishes the likelihood of developing dementia which is a great thing but it makes you wonder why this study was used to attack multivitamin use. There was not much of any chance to see any improvements from multivitamin use because of the group of men that were studied. The third, and perhaps the most disturbing aspect of this study was the fact that actual dementia or any cognitive dysfunction was never tested for. None of the participants were assessed for any level of dementia either before, during or after. How do you purport that something does not work (multivitamins) if you never test for the dysfunction you are looking to improve (cognition)?

Trial to Assess Chelation Therapy

This study set out to assess whether or not high doses of vitamins and minerals help prevent a another occurrence of a second myocardial infarction (heart attack). Two things of import to note for this one.

The first is that the people studied had a high incidence non-adherence. This is a fancy way of saying more than enough people failed to do what was requested of them ultimately affecting the data collected. In addition, the participant dropout rate was also high. It becomes a difficult task to honestly document and extract accurate information to convey to the public when so many people involved in the study fail to comply with the instructions or complete the program. It puzzles me that Eliseo Guallar and his colleagues used this study or any of the previously mentioned ones to attack vitamins and minerals.

Sunday, February 2, 2014

The Story of Cholesterol: Our Immune Systems


On a daily basis our immune systems are constantly under pressure to perform a symphony of life saving duties. Multiple levels of specialized cells and chemicals orchestrate tasks like carry messages, serve as lookouts and summon killer cells. Pathogens, inflammation, even poorly digested food make demands for the attention of our often overburdened immune systems but the indignity does not stop there for some of us. Cholesterol lowering has been the "go to" treatment for many people with the unfortunate side effect of a suppressed immune system for many.

How suppression happens

It was mentioned in a previous article that one of the few benefits of statin drugs is that it reduces inflammation in the body and indeed it does. The problem is how it goes about achieving this "accomplishment". Your immune systems is a complex work of art. A significant part of the artwork involves being able to point out infection causing pathogens to the rest of the immune system. This is accomplished by creating inflammation with a chemical known as NF-kB. We must remember that inflammation, in and of itself, is not necessarily a bad thing. Without it our bodies would suffer greatly from a lack of an alarm system (inflammation) when burglarized by infection causing materials. Problems with inflammation arises when it becomes rampant and chronic due to what we do to ourselves through certain foods, drugs or environmental exposures.

Statin drugs inhibits our bodies from making NF-kB, the chief burglar alarm of the body, by the same process in which it inhibits production of CoQ10. At first thought it would seem like a good idea to lower inflammation and by most natural standards it is. It becomes problematic when it is done with a drug that ultimately makes the immune system weaker and less responsive.

Why is NF-kB suppression a big deal?

Would it surprise you to know that some pathogens like E. Coli and Salmonella actually proliferate by suppressing the body's ability to produce NF-kB? With no alarm they can terrorize the body. There are viruses that can do the same thing or can even increase the alarm rate which causes an over response and overwhelms the system. The point is that manipulating the process to produce NF-kB generally leads to adverse or undesired results.

It is also important to point out that low cholesterol levels put people at increased risk of acquiring and dying from infections. Cholesterol itself (specifically LDL the so-called "bad cholesterol") is noted for being able to disarm 90% of toxic bacterial pathogens. Infections can take hold of the body whether cholesterol levels fall too low or through suppression of NF-kB production. In 1992 a review of 19 studies of more than 68,000 deaths found that those with low cholesterol died from respiratory and gastrointestinal infections in higher numbers than those with what is generally considered normal to high cholesterol. In addition, a study that began in 1977 called MRFIT found that men with cholesterol levels at or below 160 were four times as likely to die from AIDS as men whose levels were above 260.



The bottom line

Manipulating the immune system to prevent it from doing all or part of it's job usually leads to disastrous outcomes. Medical science has done it for years whether it be intentionally (think organ transplants) or unintentionally you can never be sure of the results. One thing is sure and that is wherever a compromised immune system exist there will be a pathogen waiting to exploit it. At that point the question becomes one of survival.

Sources include:

The Great Cholesterol Myth (Bowden and Sinatra)