- Nearly 26 million children and adults in the United States (nearly 8.5 % of the population) have diabetes
- 79 million Americans are thought to be prediabetic
- 1.9 million Americans are diagnosed with diabetes every year
- Nearly 10% of the entire U.S. population has diabetes, including over 25% of seniors
- As many as 1 in 3 American adults will have diabetes in 2050 if present trends continue
- The economic cost of diagnosed diabetes in the U.S. is $245 billion per year
- 1.9 million Americans aged 20 years or older are newly diagnosed with diabetes each year (5,205/day)
- Compared to non-Hispanic whites the risk of diagnosed is 1.2 times higher among Asian Americans, 1.7 times higher among Hispanic Americans, and 1.8 times higher among African Americans
- Diabetes is the primary cause of death for 71,382 Americans each year
- Diabetes contributes to the death of 231,404 Americans annually (combining death certificates that list diabetes as the primary and a contributing cause of death)
- $245 billion annually attributable to diagnosed diabetes, including $176 billion in direct costs and $69 billion in indirect costs (disability, work loss, premature mortality)
- People with diagnosed diabetes have health care costs 2.3 times higher than what expenditures would be in the absence of diabetes
- About 60% to 70% of people with diabetes have mild to severe forms of neuropathy
- More than 60% of nontraumatic lower-limb amputations occur in people with diabetes
- About 65,700 nontraumatic lower-limb amputations are performed in people with diabetes annually (180/day)
- Diabetes is the leading cause of kidney failure, accounting for 44% of all new cases of kidney failure
- Adults with diabetes have heart disease death rates about 2 to 4 times higher than adults without diabetes, and the risk for stroke is 2 to 4 times higher among people with diabetes
- Diabetes is the leading cause of new cases of blindness among adults aged 20–74 years
- The prevalence of diagnosed diabetes in the U.S. increased by 128% from 1988 to 2008
- Diabetes kills more Americans every year than AIDS and breast cancer combined
This blog provides alternative health views and guidance on natural remedies in addition to thought provoking insights about our everyday health lives.
Salutations!
Pages
Friday, August 8, 2014
Diabetes: A 21st Century Scourge - The Facts and Figures
Tuesday, July 29, 2014
Diabetes: A 21st Century Scourge - The Ravages of Diabetes Continued
Wednesday, March 5, 2014
The Story of Cholesterol: Energy, CoQ10 and Statins
Sunday, February 2, 2014
The Story of Cholesterol: Our Immune Systems
On a daily basis our immune systems are constantly under pressure to perform a symphony of life saving duties. Multiple levels of specialized cells and chemicals orchestrate tasks like carry messages, serve as lookouts and summon killer cells. Pathogens, inflammation, even poorly digested food make demands for the attention of our often overburdened immune systems but the indignity does not stop there for some of us. Cholesterol lowering has been the "go to" treatment for many people with the unfortunate side effect of a suppressed immune system for many.
How suppression happens
It was mentioned in a previous article that one of the few benefits of statin drugs is that it reduces inflammation in the body and indeed it does. The problem is how it goes about achieving this "accomplishment". Your immune systems is a complex work of art. A significant part of the artwork involves being able to point out infection causing pathogens to the rest of the immune system. This is accomplished by creating inflammation with a chemical known as NF-kB. We must remember that inflammation, in and of itself, is not necessarily a bad thing. Without it our bodies would suffer greatly from a lack of an alarm system (inflammation) when burglarized by infection causing materials. Problems with inflammation arises when it becomes rampant and chronic due to what we do to ourselves through certain foods, drugs or environmental exposures.
Statin drugs inhibits our bodies from making NF-kB, the chief burglar alarm of the body, by the same process in which it inhibits production of CoQ10. At first thought it would seem like a good idea to lower inflammation and by most natural standards it is. It becomes problematic when it is done with a drug that ultimately makes the immune system weaker and less responsive.
Why is NF-kB suppression a big deal?
Would it surprise you to know that some pathogens like E. Coli and Salmonella actually proliferate by suppressing the body's ability to produce NF-kB? With no alarm they can terrorize the body. There are viruses that can do the same thing or can even increase the alarm rate which causes an over response and overwhelms the system. The point is that manipulating the process to produce NF-kB generally leads to adverse or undesired results.
It is also important to point out that low cholesterol levels put people at increased risk of acquiring and dying from infections. Cholesterol itself (specifically LDL the so-called "bad cholesterol") is noted for being able to disarm 90% of toxic bacterial pathogens. Infections can take hold of the body whether cholesterol levels fall too low or through suppression of NF-kB production. In 1992 a review of 19 studies of more than 68,000 deaths found that those with low cholesterol died from respiratory and gastrointestinal infections in higher numbers than those with what is generally considered normal to high cholesterol. In addition, a study that began in 1977 called MRFIT found that men with cholesterol levels at or below 160 were four times as likely to die from AIDS as men whose levels were above 260.
The bottom line
Manipulating the immune system to prevent it from doing all or part of it's job usually leads to disastrous outcomes. Medical science has done it for years whether it be intentionally (think organ transplants) or unintentionally you can never be sure of the results. One thing is sure and that is wherever a compromised immune system exist there will be a pathogen waiting to exploit it. At that point the question becomes one of survival.
Sources include:
The Great Cholesterol Myth (Bowden and Sinatra)
Saturday, November 9, 2013
The Story of Cholesterol: The Statin Drug Nightmare Part I
Wednesday, October 23, 2013
The Story of Cholesterol: Inflammation is the villain that got away
Inflammation our friend, Inflammation our foe
Let's be fair about inflammation before we go much further. Inflammation is a natural and necessary bodily function. It serves as a marker so the immune system can know where the bad guys are. Without inflammation pathogens in the body could wonder freely and do massive damage. While acute inflammation is a natural and necessary process chronic inflammation is a killer. What causes chronic inflammation? A whole host of things actually like highly processed foods, simple carbs, too much protein (especially from animal sources), environmental toxins, medications, alcohol, etc., etc. Chronic inflammation is extremely damaging to the cardiovascular system and cholesterol has shouldered most of the blame for the last 40-50 years. And why not? If you were responsible for generating $31 billion a year in sales you would be the fall guy forever! In addition, chronic inflammation is a silent, painless killer much like hypertension and no amount of cholesterol lowering drugs can save you from it (this point will be further illustrated when the true nature of statin drugs are discussed).
Oxidative Stress and Free Radicals
Free radical is probably a term you are now familiar with but just in case you're not a brief description follows. When it comes to free radicals it helps to think of them as a pack of teenage boys at the mall roaming around just waiting to hit on receptive looking female that approaches. The whole while they are generally annoying not only the girls but anyone in the vicinity who may be watching. This pack of boys begin to upset the whole mall experience with anyone they come into contact with. That is a nuts and bolts metaphor for free radicals. They create massive amounts of inflammation and just mess up everything.
In the end chronic inflammation is of much more concern than cholesterol ever was generally. There is one scenario where cholesterol can be a bad actor but that occasion is almost exclusively dependent on free radicals and oxidative stress (imagine that). We will continue to move forward through the true story of cholesterol and cover statin drugs in particular and what they do us!
Tuesday, June 25, 2013
Slow and Steady Wins the Weight Race!
My primary goal for sharing my story is to let people know that with forethought, perseverance, and consistent change you can begin to lay the groundwork for long term and sustained weight loss. Establishing a sound eating plan and consistent activity will lay a proper foundation in case other issues need to be addressed (e.g. poor thyroid function, adrenal fatigue, the need for cleansing, chronic stress, etc.). I cannot stress enough how important it is to avoid gimmicky diet plans and supplements that could cover up or even exacerbate the issues given as an example above. Gimmicks can mask the true nature of why you are gaining weight or are unable to lose it. If you are interested I will be more than happy to provide my phase one and phase two eating plan food charts. Just email me at thoughtfulhealth@gmail.com and I will forward them to you. Go in good health!
Monday, March 25, 2013
Are you familiar with your AGE?
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What's troubling you or a loved one these days? Is it a chronic condition like diabetes, obesity, cardiovascular disease, etc. Perhaps it's something like a lack of energy, sex drive or a zest for life. Our lives today involve so much chronic stress and inflammatory foods it is a wonder we survive at all. Our lives are not meant for us to be mere survivors and there is one thing that is for sure; surviving is not thriving. Thriving involves quality of life while surviving focuses on quantity. So what does this philosophical posturing have to do with your AGE? Well, it is your AGE that partly determines how fast you "age" and it is the speed of your aging that helps determine your quality of life.
What are AGE's?
AGE stands for advanced glycated end-products. They form throughout our lives in varying degrees depending on our aptitude to live healthy. In a nut shell AGE's are molecular trash formed when glucose (blood sugar) molecules bond with free amino groups like proteins, lipids and nucleic acids that may be in the blood at the same time. These free amino groups come primarily from inflammatory foods and when they bond with glucose they change structurally and become nutritionally void and useless. Not only are they useless but they accumulate in the body where they begin to change a person from thriving to surviving (more on this in a bit).
AGE's also attach themselves to LDL cholesterol and once attached the cholesterol oxidizes making it sticky. At this point it is just a matter of time before atherosclerosis and other degenerative cardiovascular conditions begin to set in.
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Where do they accumulate?
AGE's have the ability to disrupt the life of all people but it is especially true for those who suffer with diabetes. The reason for this is because of where AGE's tend to accumulate. Diabetics suffer from a wide range of "spin-off" ailments such as heart attacks, nephropathy (kidney disease), stroke, neuropathy, eye disease and erectile dysfunction. AGE's find their way into cardiovascular tissues, nerve endings (especially those in the extremities and penis), brain tissues, and eyes. Once there they lodge themselves into the tissues and begin producing free radicals at a rate that is 50 times higher than non-glycated proteins. These free radicals alter the natural state of healthy cells in the body rendering them non-functional or potentially malignant (cancerous). The retinopathy, nephropathy, neuropathy, and atherosclerosis are directly correlated to this free radical production free-for-all. You no longer need to wonder why these conditions affect diabetics so specifically anymore. Furthermore, the free radicals produced can cause aging related issues such as thinning and graying hair, deep wrinkles in the skin, bone mineral depletion (leading to osteoporosis), a weakened immune system due to chronic inflammation, and adrenal fatigue causing loss of energy, drive and libido. The aforementioned issues can occur in anyone just in case you were thinking this only applied to diabetics. It's one for the AGE's.
How to avoid them?
High blood sugar levels over an extended period of time leads to increased glycation (associated with AGE's). Blood sugar control through exercise and a healthy eating plan, which would include eating foods that are minimally processed and fresh with low glycemic loads, will go along way in the fight against AGE's. If you are diabetic right now do not rely solely on medication for glucose control. Your blood sugar levels may be within normal range but your AGE's may still be high do to poor eating habits.
A simple way to check your rate of AGE production is through a HbA1c blood test. Traditionally used to check blood glucose levels it is also a way to gauge you AGE.
Source: Reversing Diabetes by Don Colbert, M.D.
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Wednesday, February 9, 2011
USDA Guide to the Obvious
The USDA has issued new dietary guidelines for the American consumer. These guidelines are intended to improve the health and well being of concerned citizens who wish to lead healthier lives. With heart disease and obesity reaching unheard of levels the potential guidance is needed now more than ever. And what gems has the USDA come up with? How about eating less fats and sugar, exercising more, and consuming fewer calories. Great advice for the masses but it's hardly a revelation. Most people know to do these thing already. Check out my article at QW Magazine: http://qwmagazine.co.uk/science/8793
to get my full view on this subject and a little advice to boot!