Green Tea, Pharmaceuticals and Your Hypertension

Recently an article was published on various online news outlets about green tea and its effects on a certain medication for hypertension. This same study is slated to be published in the journal Clinical Pharmacology & Therapeutics which will lend it much credibility in the eyes of many in the medical establishment. The study says, in part, that if a person is being treated for hypertension with a drug called nadolol (market name Corgard) they should not drink green tea. After careful consideration of the study findings I believe some of the issues associated with the study itself and the effects of green tea should be discussed.

"The Study"

Let us begin with the fact that this study was conducted with ten (10) people. Yes, you read that correctly and it is not a typo. Only ten people were used for this "study" and they were consuming the drug nadolol for only for two weeks. In addition, the ten individuals used in the study were between the ages of 20 and 30 with no known health issues including hypertension. None of them had high blood pressure so the effect of the green tea's interaction with the drug and its supposed effect on preventing the treatment of hypertension could not be established since it was not (and could not be) studied.

Also, no evidence of a cause and effect relationship between the drug nadolol and green tea was established. The researchers do not know why or how green tea is affecting the absorption of the drug or if it is affecting it at all. The scientist involved in the study "believe" that the antioxidant ECGC found in the tea is the culprit. As far I as can tell belief is a matter of faith and faith belongs firmly within the realm of religion and spirituality not science. If scientist wish to tell people that green tea is hazardous to their health they should diligently provide proof using the very scientific method we were all taught in grade school.

To add insult to injury the "test" subjects drank 3-4 cups of green tea per day. This represents an amount of tea that is double the average amount of green tea consumed by average tea drinking Americans. This fact makes the study dubious and misleading on its own.

Benefits of Green Tea

The sad irony of this study is that one of the many benefits of green tea is its ability to lower blood pressure. Angiotensin-converting enzymes (ACE) contributes to high blood pressure under certain situations and green tea helps to inhibit its production. Many people are on blood pressure lowering medications known as ACE inhibitors that have harmful side effects. Green tea is a natural ACE inhibitor with no known side effects. It should be noted the nadolol is not an ACE inhibitor but a beta blocker, however, the point of this message is the blood pressure relieving powers of green tea. 

Also, green tea helps to do many things like stimulate brain activity for increased clarity, reduce the chances of bacterial food poisoning by preventing the growth of E. coli and other harmful pathogens and helps to maintain proper blood glucose levels for those wishing to prevent or control diabetes. 

There are many more benefits offered by consuming green tea that are therapeutic and pleasing to the body without harmful side effects. It should, in no way, be demonized especially by such a crudely crafted study.

Conclusion

The unfortunate truth these days is that we live in a sound bite world where most people get their news from headlines. Even television news stories have taken on the cloak of superficiality and seldom report the details of anything. Not only is this practice costly but potentially devastating especially to our health. It is important more and more that we move beyond the headlines and peek behind the veil for the full story especially when it pertains to our health!

The Story of Cholesterol: The Statin Drug Nightmare Part II

Before we delve further into the nightmare that is statin drugs I think a good dose of fairness is in order. One benefit of statin drugs is that they do tend to show antioxidative abilities, decreases blood viscosity and inflammation. These are good things indeed but the trade-offs are often stupendous and some times fatal. Also, there are better, natural ways to get anti-oxidants that will not disrupt your life.

Often people who take statin drugs to lower their cholesterol experience mild to severe forms of muscle pain, fatigue, memory loss, sexual dysfunction, weakness, and cognitive dysfunction. Why is this so? It turns out that cholesterol serves many vital functions in the body and turning off production of it can lead to many serious problems as we will discuss below.

The Heart and Energy Production

Let's get to the heart of the matter. I hope you can pardon the pun but it seems to be the best place to start when discussing just how bad statin drugs tend to be. A very significant nutrient produced by the body is an enzyme called CoQ10. The highest concentrations of CoQ10 can be found in the heart because, as the most active muscle in the body, it requires much energy and CoQ10 helps to provide it. Without it the heart would cease to function properly in a relatively short amount of time. The (cruel) irony is the very drug that is meant to protect the heart can cause it the most damage.

When discussing fatigue, which can be chronic in some statin drug users, we are really discussing energy. Once again this is where CoQ10 comes in to play. Not only is the heart served by this important enzyme but all muscles in the body. It helps the metabolic processes of every cell which in turn produces energy. Limiting or eliminating production of CoQ10 can create states of fatigue that are misery inducing and life altering while at the same time weakening the heart.

The Brain

Memory loss and the inability to think clearly (cognitive dysfunction) is one of the most frightening side effects of statin drug use. Unfortunately, it is also the most frequently reported side effect. Sometimes the dysfunction is so intense it can mimic Alzheimer disease.  How does this happen? As it turns out the brain is composed of approximately 60% cholesterol. At night, as we sleep and slumber, our bodies help to repair and restore brain function with cholesterol being one of the primary ingredients. As cholesterol levels decrease so does brain function. In addition to repairs, cholesterol is a chief component in helping neurotransmitters function properly. This was conclusively demonstrated in 2009 by a Iowa State University professor by the name of Dr. Yeon-Kyun Shin. It turns out that cholesterol influences the shape and function of certain proteins in the brain that help stimulate thinking and memory.

Sexual Dysfunction

Depending upon who you ask proper brain and heart function are neck-in-neck when it comes to everyday quality of life while sexual function has its place somewhere in there. Regardless of how important sex is to you most would agree that proper sexual function is at least a close third in the three way race with the brain and heart. Cholesterol lowering medications have wrecked many sex lives with the most pronounced (and most noticeable) effect on men. All the major sex hormones are derived from cholesterol. The very hormones that causes sex lives to thrive are reduced in number and potency when cholesterol is indiscriminately cut and slashed. The hormone that is most affected is testosterone. Testosterone is a key component for proper erectile function in men and libido support for men and women (women produce small amounts of testosterone and is vitally important to all). Not to put too fine a point on the subject but mood and performance for both men and women can be adversely affected when cholesterol levels decrease. A 2009 study titled "Statins and Erectile Dysfunction: Results of a Case/Non-case Study using the French Pharmacovigilance System Database" found that men taking Crestor were two to seven times more likely to suffer from erectile dysfunction! Low testosterone levels have also been associated with decreased life expectancy and increased risk of death from cardiovascular diseases.

A bad heart, fatigue, cloudy thinking and judgement and a sex life that is left weak and uninviting is what many people have to suffer with while on statin drugs. Unfortunately, this is not all of the side effects. The others may be less troubling than what has already been mentioned here but there is one more that rarely makes the news and it has to do with our immune systems which will be addressed in the next article.

Sources include:

The Great Cholesterol Myth (Bowden and Sinatra)

The Story of Cholesterol: The Statin Drug Nightmare Part I

We have steadily climbed to the point of discussing a class of drugs known as statins. These very powerful and costly medications has reached the height of pharmaceutical popularity. Essentially a sub-industry within an industry statin drugs account for $31 billion of annual sales alone. It is estimated from sales that a staggering 15 million Americans are currently on these cholesterol lowering drugs. All the while the majority of them are suffering from side effects that range from slightly annoying to absolutely debilitating. These side effects include impaired cognitive function, sexual dysfunction, increased risk of diabetes and heart disease, lethargy and low vitamin D levels (with its associated adverse health effects when vitamin D deficiencies occur).

The history of mankind has been filled with many medical oddities that now look completely absurd to us. As far back as 1500 BC mercury was used for whatever ailed you. During the 19^th century the chief ingredient in cough syrup was heroin. And who can forget bloodletting used by the Greeks and the rest of the world right up to the 19^th century. While all of this might elicit a chuckle or two as we think of how silly “those people” were for believing in that stuff history will chuckle at us when statin drug use is reviewed for the amusement of our more enlightened descendants.

One of the many issues that surrounds the use of statin drugs is the yet unproven hypothesis that blood cholesterol is a key contributor to heart disease. You read that correctly: Cholesterol being the chief contributor to heart disease is a yet unproven hypothesis. In fact almost all studies concerning the relationship between heart disease and cholesterol either points to another culprit (e.g. inflammation), exonerates cholesterol or both. During the late ‘80’s a Dr. Russell Smith wrote a two volume review of literature associated with heart disease and diet called Diet, Blood Cholesterol and Coronary Heart Disease: A Critical Review of the Literature. It took over 600 pages of research for him to state that in the vast majority of studies reviewed there was no difference in the number of deaths between people who reduced their cholesterol and those that did not. This point will become more important as we move along.

In 1991 Dr. Smith teamed up with Dr. Edward Pinckney, the editor of four medical journals, to publish a book called The Cholesterol Conspiracy. In the book they summarized studies conducted with cholesterol lowering drugs and concluded that these drug were effective at lowering cholesterol but not deaths. Of the eight randomized and blinded trials that met their standard for study six had participants where the rate of death among the group being treated with cholesterol lowering drugs was the same or higher than the control group. That’s not very promising but it gets worse. They also looked at sixteen studies looking at reducing cholesterol using a drug and diet approach. What they found was that the death rate from all-causes in the treatment group and control was the same. In addition, the rate of death from coronary heart disease was the same or greater among the treatment group in fifteen of the sixteen trials. Yes, you read that correctly. What the good doctors demonstrated, essentially, is that there was zero benefit to lowering cholesterol when it comes to preventing adverse coronary events including death. Outside of a very narrow group of people (white males at least 48 years old who have already had one heart attack) statins have proven to have no benefit but they have proven to be extremely toxic. Part II of the statin nightmare will address specific issues that statins cause in the body.

Sources include:

The Great Cholesterol Myth

The Cholesterol Conspiracy

The Story of Cholesterol: Inflammation is the villain that got away

Let us, for the sake of illustration, imagine a crime scene. At this crime scene is a victim who is alive but unconscious and thus unable to speak. The paramedics are working tirelessly to tend to the fallen soul as a crowd of witnesses and on -lookers gather. When the police finally arrive they begin arresting the paramedics, witnesses and the on-lookers just for being at the scene. In the meantime the true culprit goes unnoticed and is allowed to continue to victimize others. If you are anything like me a sense of injustice swept over you as you pondered this scenario as it should but this is how we treat cholesterol. Cholesterol is often (but not always...we'll get to that) the unwitting witness or even the paramedic that gets blamed for doing something it had no part in while the true villain, inflammation, gets away Scot-free to continue its reign of terror. By the way, in the illustration the silent victim is our cardiovascular system.

Inflammation our friend, Inflammation our foe

Let's be fair about inflammation before we go much further. Inflammation is a natural and necessary bodily function. It serves as a marker so the immune system can know where the bad guys are. Without inflammation pathogens in the body could wonder freely and do massive damage. While acute inflammation is a natural and necessary process chronic inflammation is a killer. What causes chronic inflammation? A whole host of things actually like highly processed foods, simple carbs, too much protein (especially from animal sources), environmental toxins, medications, alcohol, etc., etc. Chronic inflammation is extremely damaging to the cardiovascular system and cholesterol has shouldered most of the blame for the last 40-50 years. And why not? If you were responsible for generating $31 billion a year in sales you would be the fall guy forever! In addition, chronic inflammation is a silent, painless killer much like hypertension and no amount of cholesterol lowering drugs can save you from it (this point will be further illustrated when the true nature of statin drugs are discussed).

Oxidative Stress and Free Radicals

Free radical is probably a term you are now familiar with but just in case you're not a brief description follows. When it comes to free radicals it helps to think of them as a pack of teenage boys at the mall roaming around just waiting to hit on receptive looking female that approaches. The whole while they are generally annoying not only the girls but anyone in the vicinity who may be watching. This pack of boys begin to upset the whole mall experience with anyone they come into contact with. That is a nuts and bolts metaphor for free radicals. They create massive amounts of inflammation and just mess up everything.

In the end chronic inflammation is of much more concern than cholesterol ever was generally. There is one scenario where cholesterol can be a bad actor but that occasion is almost exclusively dependent on free radicals and oxidative stress (imagine that). We will continue to move forward through the true story of cholesterol and cover statin drugs in particular and what they do us!

Thoughtfulhealth Product Review: SiselLean Protein/Weight Management Shake

All natural. 74 calories per scoop. Powerful nutrition. $50 bucks for a one month supply. Score!

When it comes to protein shakes it is certain that not all are created equal. In fact most protein/weight management shakes are filled with incredibly toxic and inflammation causing ingredients. It has been my observation that most people consuming these protein products are in one way or another health conscious. Whether you endeavor to lose weight or pack on extra muscle ultimately your health is affected.

Personally I fill that whatever your intentions for consuming protein shakes it should not cause you harm. If you are currently consuming a protein shake let's take a look at a few of the readily available ingredients you would find in most "off-the-shelf" products.

• Whey protein: Derived from dairy sources that are usually laced with hormones, pesticides and antibiotics. To add insult there are only two to three companies out there that actually removes the lactose for our lactose intolerant friends. Ouch!
• Isolates (soy, whey, etc): Proudly displayed on the packaging but the truth is they most companies use cheap fillers that have chemical toxins associated with them increasing inflammation and acidity in the body.
• Artificial sweeteners (sucralose, splenda, aspartame,acesulfame potassiun etc.): Drives up insulin levels in the body increasing sensitivity which leads to fat storage, slows liver function which can lead to weight gain over the long run, causes inflammation in the body increasing water and sodium retention that can lead to hypertension.
• Maltodextrin: Generally used as a sweetener there is a 95% chance that it is genetically modified and is more than likely one of 4 to 5 sugars on the label!Not all maltodextrin is used as a sweetner, however. Some products use it as a source of fiber. Knowing how the company sources their maltodextrin is important.
• GMO's: More and more evidence is mounting that products containing GMO's cause serious adverse health events. Most manufacturers will use GMO ingredients because they are cheap but while the cost to you in the near term is less the long term cost could be downright devastating!

Why I like SiselLean

I have consumed SisleLean for almost two years now and I am thoroughly convinced that it has helped me maintain a body weight and level of health and vitality I did not previously have. With proper eating habits, moderate exercise and supplementing 1 or 2 meals per day I have not had any trouble losing over 30 lbs and keeping it off. The shake is delicious without being chalky and I can feel the energy provided by the vitamins and minerals. I will discuss a few of the key ingredients to give you an idea of why I have experienced my results.

Three Quality Proteins

Whey Protein: SiselLean contains whey protein but in the right way. The protein is sourced from all natural milk (no hormones or antibiotics). Also, all the lactose is removed for those of us who are lactose intolerant. It is cold processed so the protein is not denatured making it readily available for assimilation by the body without creating inflammation. Pea and chia proteins are also used because they are easily assimilated by the body combining with the whey to ensure extensive bioavailabilty for a wide range of people.

Vitamins and Minerals

Another aspect of this shake I like very much is the vitamins and minerals it packs. Most protein shakes on the market use cheap synthetic vitamins and minerals that are usually not absorbed by the body. In fact, they usually go unrecognized which triggers an immune response. Now you have increased your level of inflammation and given the immune system extra duty! Not so with SiselLean. All of the ingredients including the vitamins and minerals are all natural (no synthetics here). In addition, the amount of protein per scoop is within normal protein consumption range for the average person. What these two things mean is you will not be causing inflammation in the body with this product. Inflammation is a key factor in weight gain and almost all chronic illnesses. In addition, there is no soy and no GMO ingredient whatsover. With over 60 vitamins and minerals to include B vitamin complex I am left energized and ready to tackle the day.  

There is so much more to this shake but I don't want to ramble on. Check out this link for more information and if you decide to order this awesome shake please know that it is not necessary to autoship your purchase. You can order as you please when you please if you opt to do so.

All natural. 74 calories per scoop. Powerful nutrition. $50 bucks for a one month supply. Score!

For additional helpful tips regarding protein follow the link provided: http://thoughtfulhealth.blogspot.com/2010/11/protein-fallacy-and-how-best-to-utilize.html

The Story of Cholesterol: The Good and Bad About "Clinical Studies"

We all have heard at one time or another some announcer on television or radio say "clinical studies have shown..." and what follows is thought or assumed to be credible information. Rightfully so when it is considered that all clinical studies follow the scientific method, right? For the most part yes but there is more to the story and studies involving cholesterol aren't always what they seem to be.

The Bad

Scientist pride themselves on the scientific method and why not. Surely if you want to propose that a thing or an outcome is "true" you have to observe it over and over again and let the data tell you what is real and what is not. The problem, from time to time, is that scientist are human and are subject to the frailties associated with being such. Pride, arrogance, and greed, especially greed, has steered many doctors and scientist astray while conducting clinical studies. We, the non-clinical study conducting types, have our part to play as well by allowing people with profit driven agendas to run these drug studies without demanding a neutral third party either run a concurrent study or run the entire study outright. After all its only our health at stake. At this point I would like to be clear about one thing: I do not mind people making a profit. I just don't like it when it is at the expense of others as opposed to the benefit of others (and this is where I digress).

Cholesterol studies have long been plagued by biased research. One of the largest and most damaging of these studies was the Framingham Heart Study (FHS). The FHS began in 1948 in Framingham, Massachusetts involving 5,000 residents of the town. Follow up was conducted with the residents for 16 years. In the end it was claimed that a direct link between cholesterol and heart disease had been firmly established. This study has been heavily cited in order to defend the "cholesterol-causes-heart disease" hypothesis and helped form a $30 billion per year cholesterol drug industry. There are several key points to consider with this study that some would find alarming and the main ones are these:

• During the study it was found that cardiovascular disease struck people with both high and low cholesterol (some levels as low as 150 mg/dl)
• Thirty years after the study it was found that people with higher cholesterol levels lived just as long or longer, on average, as those with low cholesterol

According to this study cholesterol levels seemed to imply adverse cardiovascular health only for white men who had a heart attack before the age of 48. There was very little, if any, information garnered by this study that had any broad cholesterol "doom and gloom" appeal for the general population. In fact, the study director, Dr. William Castelli acknowledged in an article written in 1992 in the journal Archives of Internal Medicine that those people who participated in the study who consumed the most saturated fat, calories and cholesterol tended to have lower blood serum cholesterol levels, were the most active and weighed the least all while not experiencing any statistically significant increase in poor cardiovascular health outcomes.

The Good

One of the longest and most comprehensive studies ever undertaken was called the Nurses' Health Study conducted by Harvard University. The goal was to determine the risk factors for cancer and heart disease. Researchers conducted an extensive analysis of over 84,000 women and made a startling discovery. They determined that there were five essential contributing factors regarding cancer and heart disease in 82 percent of the women and they are as follows:

• Smoking
• Sedentary lifestyle (little to no daily exercise)
• Excessive alcohol consumption
• Poor weight maintenance
• Diet that did not consist of whole foods, whole grains (fiber intake) and was high in sugar.

Did you notice cholesterol didn't make the list? You can believe the drug companies did not want to hear any part of this because this study definitely had the potential to interfere with profits! In the end, however,  it is a lot easier for patients and lucrative for the drug pushers to take a pill than it is to lead a healthy lifestyle so the study fell mostly on deaf ears and those who did hear and believe were ridiculed or ostracized by "scientist" backed by big money from pharmaceutical companies. 

In the next installment we will discuss the true villain when it comes to heart disease: inflammation!

If you would like to read about more studies and the cholesterol myth (in case you just can't wait for the next article) I recommend reading "The Great Cholesterol Myth" written by Dr. Jonny Bowden and Dr. Stephen Sinatra.

The Story of Cholesterol: The Beginning

One of my chief goals is to help others achieve radiant health by exposing erroneous, and often times intentionally misleading, information. There are many areas of our lives where these errors adversely impact our health and one of them is cholesterol. I must admit that prior to becoming a certified holistic health practitioner (holistic health coach) I would see the commercials for cholesterol lowering medications and agree wholeheartedly with its use. After all, one of the main ways to prevent heart disease and heart attacks was to ensure cholesterol levels were kept in check by lowering the amount in the bloodstream, right? I was convinced of this "fact" and all it took was a series of 30 second commercials to convince me and millions of others. Now the alarms are being sounded as more and more evidence would suggest that cholesterol is not what we think it is.

The Story of Cholesterol: The Beginning is the first article in what will be a continuing series on the cholesterol story and how it affects each and everyone of us. Whether you are taking a cholesterol lowering medication now or you pay insurance premiums to help cover the cost of those who do we are all paying a hefty price only to decrease what we hope to increase: our health.

The history of cholesterol as the boogie man!

Like most pharmaceutical success stories ours starts in the lab with a guy in a white coat who promises to save your life if you buy what they are selling. Enter Ansel Keys, Ph.D. He was one of the first to begin making the extraordinary and revolutionary claim that cholesterol was at the heart of cardiovascular disease (also known as the lipid hypothesis) and lowering it would reduce heart attacks and other adverse cardiovascular events. And so the myth was born and from that point in the 1950's until this very day many millions continue to believe this unsubstantiated myth (more on this in another article). The commercials haven't stopped and the myth is continuously perpetuated because statins and other cholesterol lowering drugs are a $31 billion a year industry all by itself!

What is cholesterol?

Have you ever wondered what cholesterol is and why we have it. I know personally I never stopped to consider it. The truth about cholesterol and what it does for our bodies is astounding. Here are a few things about cholesterol that you may not know:

• The brain is approximately 60% cholesterol (one of the listed side effects of statin drugs is reduced cognitive function!)
• Cholesterol is so important that it is manufactured in almost every cell in the body
• Cholesterol is an important structural molecule that is the basis of how many other molecules get built
• Cholesterol is the body's natural inflammation fighter
• Cholesterol helps to synthesize Vitamin D
• Without cholesterol we would be unable to produce bile affecting our ability to digest dietary fats
• Without cholesterol sex hormones like testosterone, estrogen and progesterone cannot be made (one of the listed side effects of statin drugs is reduced testicular and ovary size!)
• If we were able to remove all the cholesterol from our bodies we would die very quickly

As you can see cholesterol plays an important part in our health and well being. So the question becomes: How and why has cholesterol been so vilified and who profits from our media/doctor induced manic hatred for such an essential element in our lives? There is more to come shortly. Stay tuned!